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In Wessex, we support research across 30 specialty areas, including cancer, mental health, primary care and dementia. With expert clinical leaders working alongside our core team, we ensure the successful delivery of studies across Wessex.

Working with us

The NIHR supports research being delivered through 30 specialty therapy areas. Each specialty is made up of expert clinical leaders and practitioners who work at both national and local levels to ensure that studies are delivered successfully and to promote awareness of research opportunities for participants to take part in. The specialty groups also support the dialogue between the life sciences industry and charities to ensure the pipeline of research studies and to facilitate the involvement of participants to make research more effective. Visit the main NIHR website to find out what is happening nationally in the different specialties. 

In Wessex, dedicated teams support the delivery of research in each specialty. You can get in touch with our teams using the details below.

Cancer

Local team: 

Divisional and specialty lead- Dr Matthew Wheater 
Research Delivery Manager- Jocelyn Walters  
Assistant Portfolio Manager- To be confirmed                                      

Team inbox- studysupport1and3.crnwessex@nihr.ac.uk         

Cardiovascular, diabetes, metabolic and endocrine, renal and stroke

Local team: 

Divisional Clinical Lead- Dr Damian Jenkinson 
Research Delivery Manager- Alex Jones  
Assistant Portfolio Manager- Sophie Varkonyi-Clifford                         

Team inbox- studysupport2and4.crnwessex@nihr.ac.uk

Genetics, haematology, children, reproductive health and childbirth

Local team:

Divisional Clinical Lead- Dr Katrina Cathie  
Research Delivery Manager- Jocelyn Walters  
Assistant Portfolio Manager- To be confirmed                                      

Team inbox- studysupport1and3.crnwessex@nihr.ac.uk                   

Neurology, dementia and mental health

Local team:

Divisional Clinical Lead- Dr Chris Kipps  
Research Delivery Manager- Alex Jones  
Assistant Portfolio Manager- Sophie Varkonyi-Clifford                        

Team inbox- studysupport2and4.crnwessex@nihr.ac.uk

Age & ageing, dentistry, dermatology, health services research, musculoskeletal disorders, public health and primary care

Local team:

Divisional Clinical Lead- Professor Nick Francis
Research Delivery Manager- Martine Cross
Assistant Portfolio Manager- To be confirmed      

Team inbox- studysupport5.crnwessex@nihr.ac.uk

For queries regarding the below specialties, please contact the local team:

  • Anaesthesia, peri-operative medicine & pain management

  • Critical care

  • Ear, Nose and Throat (ENT)

  • Gastroenterology

  • Hepatology

  • Infection

  • Trauma and emergency care

  • Ophthalmology

  • Respiratory

  • Surgery

Local team:

Divisional Clinical Lead- Dr David Pogson
Research Delivery Manager- Clare Rook 
Assistant Portfolio Manager- Jazz Bartholomew

Team inbox- studysupport6.crnwessex@nihr.ac.uk 

Social care

Local team:

Clinical Lead- To be confirmed 
Research Delivery Manager- Alex Jones   

Contact information- alex.jones@nihr.ac.uk 

Cancer research in Wessex 

Wessex is home to 2.7 million people, eight acute hospital trusts, two cancer centres, an experimental cancer medicine centre and the UK’s first cancer centre for immunotherapy. We develop and deliver world class cancer clinical trials and are passionate about offering innovative treatments to as many patients as possible.

Key achievements

  • Wessex is consistently one of the top performing Clinical Research Networks (CRNS) in the country
  • In the 2019/20 financial year, we delivered over 200 cancer research studies in Wessex, with almost 4,000 participants recruited.
  • Our engaged regional multidisciplinary team and our vast research portfolio across a range of cancer sub-specialties provide many opportunities for patients to participate in research. 
  • Our web-based platform, CancerLine, increases accessibility to research opportunities for both clinical teams and patients. 

Local infrastructure

Wessex is home to:

Digital infrastructure

CancerLine is a web-based platform used to enable patient access to research opportunities. It is primarily aimed at clinical teams across Wessex, allowing them to view the real time cancer trial portfolio across all Wessex acute trusts. The site aims to enhance Network working, further engender the clinical research culture and improve patient access and recruitment to trials. It is anticipated there will be increased ‘across Trust’ referrals, a national cancer specialty objective. 

The website is accessible to the public, informing patients and their carers of available opportunities – again a driver of increased clinical trial recruitment and engagement. This platform has many filters to help users find the appropriate study for them. The 16-24 age filter has recently been introduced to maximise opportunities for the younger population.

Case studies 

Paediatric Oncology Immunotherapy Studies

Our ground-breaking immunotherapy trials are giving new hope to babies and children living with neuroblastoma, a rare type of cancer. Dr Juliet Gray, Associate Professor in Paediatric Oncology at the University, is leading new UK immunotherapy studies which are looking at improving neuroblastoma treatments and their effectiveness. Find out more about her work

Idiopathic Pulmonary Fibrosis (IPF) Research

Researchers at the NIHR Southampton Respiratory Biomedical Research Unit have shown that the lung cancer drug Nintedanib can slow the progression of idiopathic pulmonary fibrosis (IPF), a condition in which the lungs become scarred and breathing becomes increasingly difficult. Find out more

Contact Us

To find out more about our work, please get in touch with a member of the team on studysupport1and3.crnwessex@nihr.ac.uk

  • Divisional Clinical Lead- Dr Matthew Wheater
  • Research Delivery Manager- Jocelyn Walters
  • Industry Operations Manager- Tom Simpson
  • Assistant Portfolio Manager- Lucy Dowden
  • Industry Research Coordinator- Katherine Shawley

 

Respiratory research in Wessex

"Respiratory conditions affect at least 1 in 5 people and are among the third most commonly reported illnesses in the UK.  They can be difficult to treat and have a huge impact of peoples’ quality of life. Researchers in Wessex lead on and participate in research programmes in obstructive airways diseases (Asthma/COPD), Interstitial lung diseases, infective lung diseases (Cystic Fibrosis, TB), pleural diseases and pandemics (COVID-19).
 
"Respiratory research in Wessex encompasses exploring novel technologies to diagnose and treat lung diseases, genetics, molecular pathophysiology, translational research and clinical trials.  Our research leads have excellent track records of recruiting into both commercial and non-commercial studies and working with funding bodies and collaborations, both national and international. We have supported the delivery of the world's largest digital physiological technology study ever undertaken- the VISION-D study which recruited 8,585 people to support the development of a camera-based technology to remotely measure patient observations."
 
Dr Hitasha Rupani, CRN Wessex Respiratory Specialty Lead 

 

Key achievements

  • We have a strong collaborative approach to respiratory research, working with both primary and secondary care sites.
  • In the 2019/20 financial year, 51 respiratory research studies were adopted onto the NIHR portfolio. Wessex was the top recruiting Clinical Research Network in the country for respiratory research, with almost 5,000 patients recruited to studies.
  • In 2014, the Wessex region was awarded funding to deliver a five year programme aimed at improving respiratory outcomes for local patients. 

Local infrastructure

Wessex is home to:

Case studies

MISSION ABC at Portsmouth Hospitals University NHS Trust (PHU)

The research team at PHU have been leading the delivery of a series of research projects aimed at improving the care pathway for patients living with respiratory conditions. Through a successful partnership with The Health Foundation and the Wessex Academic Health Science Network, PHU have tested and evaluated MISSION – a novel clinic model which delivers high-quality integrated care for patients. This model is replicable by other specialist teams in partnership with their local community partners and a toolkit has been developed to allow outside research teams to deliver their own MISSION clinic. Find out more about this research project or access the toolkit

Contact Us

To find out more about our work, please get in touch with a member of the team on studysupport6.crnwessex@nihr.ac.uk

Clinical Research Specialty Lead- Dr Hitasha Rupani
Divisional Clinical Lead- Dr David Pogson
Research Delivery Manager- Clare Rook
Industry Operations Manager- Tom Simpson
Assistant Portfolio Manager- Jazz Bartholomew
Industry Research Coordinator- Katherine Shawley

Hepatology Research in Wessex

Wessex hosts two of the top performing research centres for commercial and non-commercial hepatology research, University Hospital Southampton (UHS) and Portsmouth Hospitals University NHS Trust. Local infrastructure and strong collaborative links across research teams enables the delivery of early to late phase trials effectively.  Over the last five years, local teams have consistently delivered commercial research projects to time and target (75%+ RTT).

Key Achievements

  • In the 2019/20 financial year, Wessex participated in 26 hepatology research studies with almost 300 participants recruited.
  • 75% of NIHR commercial portfolio studies recruited to time and target (2015-2019).

Local Infrastructure

  • MRI for non-invasive diagnosis of fibrosis/NAFLD within UHS
  • Specialist Hepatocellular carcinoma oncology and radiology offered at UHS
  • A dedicated clinical research facility with Phase I clinical trials capability based at UHS
  • UKCRC Registered Clinical Trials Unit, Southampton, delivering a portfolio trials that are internationally and nationally outstanding in the priority areas of cancer, primary care, supportive care, nutrition, respiratory, critical care and liver disease.
  • Biomedical Imaging Unit, Southampton General Hospital, provides research and diagnostic services in high quality and high resolution light and electron microscopy. Their equipment includes state-of-the-art transmission and scanning electron microscopes, laser scanning confocal microscopes, a virtual slide scanning system, live cell imaging facilities, 2D and 3D analysis and rendering workstations and general photo microscopes.

Case Studies

Hepatitis C on Isle of Wight (IOW)

In 2014, patients on the IOW with a diagnosis of Hepatitis C (HCV) could only be treated on the mainland. The geographical isolation of the Island had meant that many patients were unable to attend appointments or complete treatment.

At the time this represented a service inequality compared to patients on the mainland. Additionally, the Isle of Wight was considered to be an ideal location to test the potential feasibility of achieving the micro-elimination of HCV through treatment.

Accordingly, an innovative Island based testing and treatment model was developed using community pharmacies and local hospital services, which was assessed with a service and cost-effectiveness evaluation. Alongside this, a network-based modelling study took advantage of the unique geographical characteristics of the Isle of Wight to test the most efficient approach to achieving elimination.

The project was funded by two research grants from Gilead LTD totalling over £50,000 and a PhD fellowship from the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) programme. Twenty community pharmacies participated in the programme and HCV treatment was relocated to St Mary’s Hospital on the Isle of Wight and the local drug and alcohol support service.

The project led to the increased identification of Hepatitis C infections and increased engagement with treatment services by infected individuals. The project led directly to four peer-reviewed publications. One published in 2019 was the first to demonstrate the cost-effectiveness of community pharmacy based testing for Hepatitis C. Another, published in 2020, is the first study to demonstrate and quantify how targeted treatment at certain individuals prevents onward transmission of the virus.

Six years after the study started the treatment service on the Isle of Wight continues and to date over fifty people have been treated locally. The project funded the purchase of equipment called a Fibroscanner™. This remains in use at St Mary’s hospital and has been transformative at improving access to Hepatitis C treatment and for identifying undiagnosed liver cirrhosis due to other causes.

The Isle of Wight Hepatitis C project has demonstrated that research conducted in a small, isolated area of the Wessex region can have a sustainable far-reaching academic and clinical impact.

Contact Us

To find out more about our work, please get in touch with a member of the team on studysupport6.crnwessex@nihr.ac.uk

Specialty Lead- Dr Richard Aspinall
Divisional Clinical Lead- Dr David Pogson
Research Delivery Manager- Clare Rook
Industry Operations Manager - Tom Simpson
Assistant Portfolio Manager- Jazz Bartholomew
Industry Research Coordinator – Bella Warr

 

Introduction

Wessex is home to 2.7 million people and eight acute hospital trusts. We develop and deliver world class clinical trials and are passionate about offering innovative treatments and procedures to as many patients as possible. 

Key Achievements

  • Wessex is consistently one of the top performing Clinical Research Networks in the country for paediatric research.
  • In the 2019/20, we delivered over 150 paediatric, reproductive Health and childbirth research studies in Wessex, with just over 9,300 participants recruited.
  • An increase in locally-led reproductive health and childbirth research improving care for mothers and babies in the region.
  • One of our biggest successes is having an engaged regional multidisciplinary team across both specialties as well as having vast research portfolios providing many opportunities for patients.

Local Infrastructure

Digital Infrastructure

Healthier Together - a web-based platform that provides useful clinical resources and advice for children, parents and pregnant women. Information about participation in research and available studies is also listed. We anticipate this will improve patient awareness, access and recruitment. 

Case Studies

Reproductive health and childbirth 

CRN Wessex were the top recruiter for The Cessation in Pregnancy Incentives Trial, which explored ways to help women quit smoking during pregnancy.

Poole Hospital contributes to international research improving the experience of fathers in neonatal units, which champions better communication and engagement to help fathers bond with their babies.

Paediatrics

Infectious disease specialists in Southampton are working with young people across Hampshire to potentially shape the future of routine teenage meningitis vaccinations in the UK.

Professor Saul Faust, director of CRN Wessex and the NIHR Southampton Clinical Research Facility, and his team are travelling to colleges around the county to vaccinate sixth-form students aged 16 to 19. Each student will be immunised against meningitis B, the most common cause of meningococcal disease in the age group, with one of two licensed vaccines. 

The Paediatric post pneumococcal conjugate vaccine study is one of Solent NHS Trust’s highest recruiting studies. Solent has been involved in recruitment for several years and recruited 471 participants in 2019/20.

Contact Us

To find out more about our work, please get in touch with a member of the team on studysupport1and3.crnwessex@nihr.ac.uk.

● Divisional Clinical Lead- Dr Katrina Cathie
● Research Delivery Manager- Jocelyn Walters
● Industry Operations Manager- Tom Simpson
● Assistant Portfolio Manager- Lucy Dowden
● Industry Research Coordinator- Bella Warr