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Use the options on the right-hand side to filter this list of studies by different Patient Recruitment Centres and/or by study status (open/upcoming/closed).

    TRIUMPH-4

    Study date: 09 January 2024

    Status: Open

    TRIUMPH-4 is a clinical research study for people with excess weight and knee osteoarthritis pain. The study will test how safe and well an investigational medicine (a medicine being studied) works for weight management and knee osteoarthritis pain.

    If you would like further information, contact: PRCLeicester@uhl-tr.nhs.uk

    TRIUMPH-1

    Study date: 21 December 2023

    Status: Open

    TRIUMPH-1 is a new clinical research study for people with excess weight. The study will test how safe and well an investigational medicine (a medicine being studied) works for weight management. 

    If you would like further information, contact: PRCLeicester@uhl-tr.nhs.uk.

    SYNCHRONIZE™-CVOT

    Study date: 19 December 2023

    Status: Open

    The SYNCHRONIZE™-CVOT Trial is testing an investigational medication to see whether it is safe and if it has any effect on the heart, blood vessels, and/or body weight. We plan to enrol a wide variety of participants. This is because medications may affect people differently based on their age, sex, gender, and race/ethnicity

    If you would like further information, contact: PRCLeicester@uhl-tr.nhs.uk

    RADIAL

    Study date: 29 September 2023

    Status: Open

    This Pan-European pilot study compares Decentralised Clinical Trial (DCT) and hybrid approaches to conventional clinical trial approaches in patients with type 2 diabetes treated with a long-lasting insulin, called Toujeo®.

    If you would like further information, contact: PRCLeicester@uhl-tr.nhs.uk or nuth.PRCNewcastle@nhs.net who are running the study.

    RADIANT

    Study date: 14 September 2023

    Status: Open

    This study aims to find out if the treatment of type 1 diabetes is better with a new device called Omnipod® 5 compared to injections. The Omnipod® 5 is a tubeless insulin pump, also called a Pod, which delivers insulin constantly through a tiny plastic tube that sits under the skin. Pods are controlled by an app on a study-provided phone. It takes information from a blood sugar sensor called FreeStyle Libre 2 to adjust insulin delivery and keep your sugars in the healthy range.

    If you would like further information, please contact: 0116 258 8575 or email: T1andTechResearch@uhl-tr.nhs.uk

    FreeDM2

    Study date: 14 July 2023

    Status: Open

    This study uses the FreeStyle Libre 3 Flash Continuous Glucose Monitoring System and is for people with type 2 diabetes who manage their blood sugar levels using long-acting, background insulin and other glucose-lowering medications, including drugs known as SGLT2 inhibitors or GLP-1RA. This study will help us to learn more about using continuous glucose monitoring systems in people with type 2 diabetes.

    If you would like further information, please contact: 0116 258 8575 or email: freedm2@uhl-tr.nhs.uk

    REDEFINE 3

    Study date: 09 May 2023

    Status: Open

    The study, REDEFINE 3, is looking at a combination of two medicines. REDEFINE 3 is needed to help us understand how effective these two medicines are for reducing cardiovascular events, such as heart attacks and stroke. This study is funded and sponsored by Novo Nordisk. 

    This study is open at PRC: Bradford, PRC: Leicester, PRC: Exeter. And upcoming at PRC: Blackpool and PRC: Newcastle.

    To find out more about the REDEFINE-3 study, please visit www.redefine3.org.uk or contact the team: prc@nihr.ac.uk

    REDEFINE 2

    Study date: 02 March 2023

    Status: Closed

    The REDEFINE 2 study will look at a combination of two medicines, which have been shown in previous clinical trials to help people lose weight. REDEFINE 2 will look at how well this combined medication works at helping people with type 2 diabetes and excess body weight to lose weight compared to placebo (dummy) medicine.

    If you would like further information, contact: PRCLeicester@uhl-tr.nhs.uk

    SURMOUNT MMO

    Study date: 14 February 2023

    Status: Closed

    This study will look at the effect of a new medicine, when taken once a week on the health and life expectancy of adults living with excess body weight. It is currently used for patients with type 2 diabetes, where it has been shown to reduce body weight.

    If you would like further information, contact: PRCLeicester@uhl-tr.nhs.uk

    PROGRESS

    Study date: 30 January 2023

    Status: Closed

    The PROGRESS study is a global assessment of the prevalence of oral human papillomavirus (HPV) infection, which is the name of a very common group of viruses

    If you would like further information, please contact: PRCLeicester@uhl-tr.nhs.uk