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CRN East Midlands COVID-19 Studies



CRN East Midlands is working with partners across the region to deliver Urgent Public Health research studies into COVID-19. These studies are designed to enable us to better understand and tackle COVID-19, including aiding with the development of treatments and a vaccine.

You can find out more about each of the COVID-19 research studies currently in operation across the East Midlands below:

Accord 2

This new, national clinical trial initiative is seeking to accelerate the development of new drugs for patients hospitalised with COVID-19. If positive early results are seen, these drugs will advance rapidly into large-scale clinical trials.

Find out more.


This study is investigating the effectiveness of a new vaccine that has been developed for COVID-19.

Find out more.


This study is evaluating the diagnostic accuracy of IVDs (in vitro diagnostic devices) for COVID-19 infection and monitoring the immune response.

Find out more.


This study is aiming to determine whether specific genes can cause susceptibility to COVID-19, which could help to determine and prioritise treatments used in response to the pandemic.

Find out more.


This study is investigating for how long people are infectious with COVID-19, and what puts people at higher risk of infection.

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Neonatal Complications of Coronavirus Disease

This study is analysing how COVID-19 affects babies, including symptoms and prevalence.

Find out more.


This study is collecting data about the impact of COVID-19 during pregnancy to help better understand the disease and to guide improvements in patient care for pregnant women.

Find out more.


This study, which is operating through GP practices, is seeking to determine whether existing treatments could be used to help people with COVID-19 symptoms and prevent them from needing to be hospitalised. 

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This study, which takes place in hospitals, is exploring whether a range of possible treatments are more effective in helping COVID-19 patients recover than the usual standard of hospital care, which all patients receive.

Find out more.

RECOVERY RS (Respiratory Support)

This study is designed to compare the effectiveness of three ventilation methods for COVID-19 patients, exploring whether they help patients recover more quickly than those receiving standard hospital care.

Find out more.


This study is targeted at patients in intensive care units, and is looking at the effect a number of drugs have on patients with significant community-acquired pneumonia.

Find out more.

UKOSS: Pandemic Influenza in Pregnancy

This study is seeking to understand the impact of COVID-19 on pregnancy, including how treatment of the disease affects outcomes for mother and infant.

Find out more.

What’s the Story

This study is seeking to determine how many children and young adults in different regions of England have had COVID-19 by looking for specific antibodies in a single blood sample.

Find out more.