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CRN East Midlands COVID-19 Studies



CRN East Midlands is working with partners across the region to deliver Urgent Public Health research studies into COVID-19. These studies are designed to enable us to better understand and tackle COVID-19, including aiding with the development of treatments and a vaccine.

You can find out more about each of the COVID-19 research studies currently in operation across the East Midlands below:

Accord 2

This new, national clinical trial initiative is seeking to accelerate the development of new drugs for patients hospitalised with COVID-19. If positive early results are seen, these drugs will advance rapidly into large-scale clinical trials.

Find out more.

Coronavirus infection in immunosuppressed children

This study is investigating the impact of COVID-19 on children who are immunosuppressed, and enables children or parents to self-record their experiences online each week.

Find out more.


This study is investigating urgent COVID-19 questions including for how long people are infectious, and what puts people at a higher risk of infection.

Find out more.


This study is aiming to determine whether specific genes can cause susceptibility to COVID-19, which could help to determine and prioritise treatments used in response to the pandemic.

Find out more.


This study is collecting data about the impact of COVID-19 during pregnancy to help better understand the disease and to guide improvements in patient care for pregnant women.

Find out more.

The PRIEST study

This study is aiming to optimise the triage of patients using the emergency care system with suspected respiratory infections during the COVID-19 pandemic, including whether or not patients should be admitted to hospital.

Find out more.


This study, which is operating through GP practices, is seeking to determine whether existing treatments could be used to help people with COVID-19 symptoms and prevent them from needing to be hospitalised. 

Find out more.


This study, which takes place in hospitals, is exploring whether a range of possible treatments are more effective in helping COVID-19 patients recover than the usual standard of hospital care, which all patients receive.

Find out more.

RECOVERY Respiratory Support

This study is designed to compare the effectiveness of three ventilation methods for COVID-19 patients, exploring whether they help patients recover more quickly than those receiving standard hospital care.

Find out more.


This study is targeted at patients in intensive care units, and is looking at the effect a number of drugs have on patients with significant community-acquired pneumonia.

Find out more.

SARSCoV2 infection

This study is investigating whether an inhaled drug can prevent or reduce infection of the lungs in patients with COVID-19.

Find out more.

UKOSS: Pandemic Influenza in Pregnancy

This study is seeking to understand the impact of COVID-19 on pregnancy, including how treatment of the disease affects outcomes for mother and infant.

Find out more.

What’s the Story

This study is seeking to determine how many children and young adults in different regions of England have had COVID-19 by looking for specific antibodies in a single blood sample.

Find out more.